To study the frequency of dysplasia and carcinoma in cervical smears, their clinical presentation and their correlation with koilocytosis, presence of x-chromatin and their association with HSV - 2. (Record no. 543)

MARC details
000 -LEADER
fixed length control field 02215 a2200241 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220906184545.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 190515b ||||| |||| 00| 0 eng d
060 ## - NATIONAL LIBRARY OF MEDICINE CALL NUMBER
Classification number THS-00076
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Bashyal, Reeta.
9 (RLIN) 1676
245 ## - TITLE STATEMENT
Title To study the frequency of dysplasia and carcinoma in cervical smears, their clinical presentation and their correlation with koilocytosis, presence of x-chromatin and their association with HSV - 2.
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Date of publication, distribution, etc. c2001.
300 ## - PHYSICAL DESCRIPTION
Extent 76p. :
500 ## - GENERAL NOTE
General note Thesis Report.
520 ## - SUMMARY, ETC.
Summary, etc. ABSTRACT: A total of 1,106 cases were studied during a one year period from 1/11/2056 to 30/10/2057. Majority of the lesions were Fast smears constituting 91.0%, Cervical intraepithelial neoplasia [CIN] and squamous cell carcinoma [SCC] cervix constituted 8.0 and 1.0% respectively. The percentage of different grades of CIN being CIN I 85.0%, CIN I-II 5.0%, CIN II 4.0%, CIN II-III 2.0% and CIN III 4.0%. Thirty cases were taken as a study group. The commonest age group for CIN was 31-40 years 80.0% and for Carcinoma cervix above 50 years 63.0%. The most common risk factors were marriage before 20 years of age 80.00% and a low socioeconomic status 70.0%. The common presenting feature in CIN was pain lower abdomen 88.0% followed by whitish discharge per vagina and anorexia 60.0% each. Similarly in Carcinoma cervix pain lower abdomen 80.00% followed by weight loss 60.0% were the common presenting symptoms. Koilocytic change was seen in 41.0% of the cases of CIN I. The incidence of x-chromatin positivity gradually decreased is the lesion advanced, the p value between CIN I and CIN II (p=<0.02), CIN I and CIN III (p=0.00) and between CIN III and carcinoma cervix (p=<0.004) being significant. An association with HSV-2 was seen in 10.6% caes of CIN I, 33.3% cases of CIN III and 40.0% cases of Carvinoma cervix with a gradual rising antibody time of 1:2 in CIN I, 1:7 in CIN III and 1:7 to 1:9 in Carcinoma cervix respectively.
546 ## - LANGUAGE NOTE
Language note Eng.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Dysplasia.
9 (RLIN) 1922
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Carcinoma.
9 (RLIN) 1923
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cervical Smears.
9 (RLIN) 1924
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Koilocytosis.
9 (RLIN) 1925
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://nhrc.gov.np/contact/">http://nhrc.gov.np/contact/</a>
Link text Visit NHRC Library
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme National Library of Medicine
Koha item type Thesis Report
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
    National Library of Medicine     Nepal Health Research Council Nepal Health Research Council Reference 07/15/2012   THS-00076/BAS/2001 THS-00076 07/15/2012 07/15/2012 Thesis Report

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