TY  - BOOK
AU  - Hulley,Stephen B
TI  - Designing clinical research
SN  - 9780781782104
AV  - R853.C55 D47 2007
U1  - 610.72 22
PY  - 2007///
CY  - Philadelphia, PA
PB  - Lippincott Williams & Wilkins
KW  - Clinical trials
KW  - Medicine
KW  - Research
KW  - Methodology
KW  - Epidemiology
KW  - Epidemiologic Methods
KW  - Research Design
KW  - Clinical Trials as Topic
N1  - Book; Includes bibliographical references and index; Getting started: the anatomy and physiology of clinical research; Stephen B. Hulley, Thomas B. Newman, and Steven R. Cummings --; Conceiving the research question; Steven R. Cummings, Warren S. Browner, and Stephen B. Hulley --; Choosing the study subjects: specification, sampling, and recruitment; Stephen B. Hulley, Thomas B. Newman, and Steven R. Cummings --; Planning the measurements: precision and accuracy; Stephen B. Hulley, Jeffrey N. Martin, and Steven R. Cummings --; Getting ready to estimate sample size: hypotheses and underlying principles; Warren S. Browner, Thomas B. Newman, and Stephen B. Hulley --; Estimating sample size and power: applications and examples; Warren S. Browner, Thomas B. Newman, and Stephen B. Hulley --; Designing a cohort study; Steven R. Cummings, Thomas B. Newman, and Stephen B. Hulley --; Designing cross-sectional and case-control studies; Thomas B. Newman [and others] --; Enhancing causal inference in observational studies; Thomas B. Newman, Warren S. Browner, and Stephen B. Hulley; Designing a randomized blinded trial; Steven R. Cummings, Deborah Grady, and Stephen B. Hulley --; Alternative trial designs and implementation issues; Deborah Grady, Steven R. Cummings, and Stephen B. Hulley --; Designing studies of medical tests; Thomas B. Newman [and others] --; Utilizing existing databases; Deborah Grady and Norman Hearst --; Addressing ethical issues; Bernard Lo --; Designing questionnaires and interviews; Steven R. Cummings and Stephen B. Hulley --; Data management; Michael A. Kohn --; Implementing the study and quality control; Deborah Grady and Stephen B. Hulley --; Community and international studies; Norman Hearst and Thomas E. Novotny --; Writing and funding a research proposal; Steven R. Cummings and Stephen B. Hulley
N2  - Providing a practical guide to planning, tabulating, formulating, and implementing clinical research, with an easy-to-read, uncomplicated presentation. This edition incorporates current research methodology, including molecular and genetic clinical research, and offers an updated syllabus for conducting a clinical research workshop. Emphasis is on common sense as the main ingredient of good science. The book explains how to choose well-focused research questions and details the steps through all the elements of study design, data collection, quality assurance, and basic grant-writing. All chapters have been thoroughly revised, updated, and made more user-friendly
ER  -