TY  - GEN
AU  - Shrestha, Sanjay.
TI  - Preanesthetic medication with oral midazolam for pediatric surgical procedures
PY  - 2002///
KW  - Preanesthetic
KW  - Medication
KW  - Midazolam
KW  - Pediatric surgical
N1  - Thesis Report
N2  - ABSTRACT:  Purpose: This was  a double blind, placebo-controlled, randomized study conducted at Kanti Children's Hospital in 60 children aged 1 to 6 years old with ASA grades I and II. Ther prupose of this study was to see the efficacy of oral midazolam as a premedication in children of this age group.  Methodology: 60 patients undergoing elective surgeries were randomized into two groups. The study group (group A) was given oral midazolam 0.5 mg/kg (Mixed in fruit juice) and the control group (group B) was given just the fruit juice (placebo) before bringing them inside the operating theatre. They were evaluated for ease of separation from their parents, for ease of induction by facemask, and for recovery time from anesthesia.  Results: It was found that in group A- 96.7% of children (29 out of 30) showed satisfactory parent-child separation, while in group B - only 53.3%  of children (16 out of 30) showed satisfactory separation (P<0.05). Similarly in group A - 73.3% of children (22 out of 30) had satisfactory induction, whereas in group B - only 33.3% of children (10 out of 30) had satisfactory induction (p<0.05). The recovery time from general anesthesia did not differ in the two groups. No significant perioperative complications directly related to oral midazolam were noted.  Conclusion:   It was concluded that oral miodazolam is a convenient and efficacious method of premedication in children undergoing general anesthesia. Parent - child separation and induction of anesthesia was smooth and recovery was uneventful in children premidicated with oral midazolam.
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