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008			200723b ||||| |||| 00| 0 eng d
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060			_aTHS-00558
100			_aJoshi,Aishana. _93582
245			_aPearl score in predicting ninety day outcome in patients with acute exacerbation of COPD at tertiary care teaching hospital.
260			_cc2019.
300			_a74p.
500			_aThesis Report.
520			_aABSTRACT: Introduction: Acute exacerbation of COPD is one of the most common reasons for frequent hospital admission. The 90 days post discharge period after acute exacerbation covers the high risk period associated with substantial risk or death, adverse quality of life and high health care costs. The aim of this study was to assess the post discharge 90 days outcome of patients admitted with acute exacerbation of COPD using the PEARL score. Methods: A prospective cohort study was conducted at Tribhuvan University Teaching hospital, Kathmandu, Nepal from September 2018 to August 2019. Patients admitted with acute exacerbation of COPD was stratified using the PEARL score and post discharge 90 days outcome was assessed. Data entry and analysis was done in SPSS version 20.0. Both descriptive and inferential statistics were performed. Univariate analysis was performed using frequency, proportion, mean and standard deviation while bivariate analysis was performed using ANOVA and Chi-square test. Results: A total of 102 patients admitted in medical ward with acute exacerbation of COPD were included in the study. The mean age of patients was 70.54 ± 10.85 years with range from 45 to 98 years. There were 53.9% male patients. The intermediate risk and high risk PEARL groups had the highest proportion of readmission within 90 days of discharge from hospital which was found to be 52.3% and 50% respectively. The high risk PEARL group had the highest proportion of death within 90 days (11.1%). The difference in these outcomes among the PEARL groups was found to be statistically significant (p-value < 0.005). 14 Conclusion: PEARL score is a highly valuable tool that uses routinely available indices to predict 90 days risk of readmission or death in patients admitted with acute exacerbation of COPD. It can effectively guide clinicians to identify the patients at particular risk for clinical decision making, appropriate resource allocation and post discharge planning. Keywords: COPD; exacerbation; PEARL score
650			_aCOPD. _92073
650			_aExacerbation. _93583
650			_aPEARL score. _93584
856			_uhttp://nhrc.gov.np/contact/ _yVisit NHRC Library
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999			_c2876 _d2876