000			02625nam a22002297a 4500
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040			_eNLM
060			_aRES-01116
100			_aShrestha,Deepti.
245			_aPrescribing pattern of antibiotic among hospitalized patients with urinary tract infection in tertiary care hospital.
260			_cc2022.
300			_avii,36p.
500			_aResearch Report.
520			_aABSTRACT: INTRODUCTION Urinary tract infection (UTI) is one of the most common bacterial infections worldwide. It has become one of the most common cause for the hospitalization and sepsis. The most common causative organism of UTI are Escherichia coli (E.coli), Enterococcus, Klebsiella, Pseudomonas and other Enterococcus or Staphylococcus species. UTI is generally treated with antimicrobial agents and fluids. This study was conducted to study the prescribing pattern of antibiotic among hospitalized patients with urinary tract infection. METHODS This cross-sectional study was conducted in Nepal Medical College Teaching Hospital (NMCTH), Attarkhel, Kathmandu from January 2022 to April 2022. Patients aged 18 years or above of both sex, admitted to various departments with the provisional diagnosis of UTI were included in the study. RESULTS Out of 146 patients admitted with a diagnosis of UTI, more than half were females (98, 67.1%). Most commonly affected age groups range from 18-30 years (40, 27.4%). Diabetes mellitus (DM) was the commonest risk factor in 36 (24.6%) patients followed by renal stone (23, 15.7%) and pregnancy (22, 15.1%). The most commonly prescribed antibiotics during hospital stay was cephalosporin in 102 (69.9%) patients followed by combination of penicillin and beta lactamase inhibitors (31, 21.2%) and fluroquinolones (15, 10.3%). Ceftriaxone (78, 53.4%) alone was the most commonly prescribed antibiotic as empirical therapy followed by combination of piperacillin and tazobactam (22, 15.1%). One hundred and forty four (78.6%) patients were prescribed antibiotics from watch group followed by access group (21, 11.5 %). CONCLUSION Cephalosporin was the commonest antibiotic group prescribed in hospitalized patient where ceftriaxone was commonly prescribed as an empirical therapy. Among AWaRe classification, antibiotics from Watch group were commonly prescribed.
650			_aPrescribing pattern.
650			_aAntibiotic.
650			_aHospitalized patients.
650			_aUrinary tract infection.
856			_yhttp://www.nhrc.gov.np/
942			_2NLM _cRR
999			_c3207 _d3207