000			04158cam a22004934a 4500
001			71223173
003			OCoLC
005			20240722140443.0
008			060824s2007 paua b 001 0 eng
010			_a2006028271
020			_a9780781782104
020			_a0781782104
020			_z2900781782103
024	3		_a9780781782104
035			_a(OCoLC)71223173 _z(OCoLC)493437707 _z(OCoLC)992219047 _z(OCoLC)1167061986
040			_aDNLM/DLC _beng _cDLC _dNLM _dBAKER _dC#P _dYDXCP _dBTCTA _dLVB _dIG# _dTTS _dDEBBG _dOCLCQ _dOCL _dZWZ _dOCLCQ _dSTJ _dOCLCF _dWUM _dOCLCO _dOCLCQ _dOCLCO _dI8M _dOCLCO _dTHHCU _dXFF _dCNUTO _dVGM _dNJK _dTHHCU _dNJR _dOCLCA _dOCLCQ _dVVL _dFQM _dOCLCQ _dQE2 _dCASUM _dUKEHC _dOCLCO
042			_apcc
050	0	0	_aR853.C55 _bD47 2007
060	0	0	_a2007 A-481
060	1	0	_aWA 950 _bD457 2007
082	0	0	_a610.72 _222
086	0		_aHEA4066
245	0	0	_aDesigning clinical research / _cStephen B. Hulley [and others]
250			_a3rd ed
260			_aPhiladelphia, PA : _bLippincott Williams & Wilkins, _cc2007.
300			_axv, 367 pages : _billustrations ; _c26 cm
336			_atext _btxt _2rdacontent
337			_aunmediated _bn _2rdamedia
338			_avolume _bnc _2rdacarrier
500			_aBook.
504			_aIncludes bibliographical references and index
505	0	0	_tGetting started: the anatomy and physiology of clinical research / _rStephen B. Hulley, Thomas B. Newman, and Steven R. Cummings -- _tConceiving the research question / _rSteven R. Cummings, Warren S. Browner, and Stephen B. Hulley -- _tChoosing the study subjects: specification, sampling, and recruitment / _rStephen B. Hulley, Thomas B. Newman, and Steven R. Cummings -- _tPlanning the measurements: precision and accuracy / _rStephen B. Hulley, Jeffrey N. Martin, and Steven R. Cummings -- _tGetting ready to estimate sample size: hypotheses and underlying principles / _rWarren S. Browner, Thomas B. Newman, and Stephen B. Hulley -- _tEstimating sample size and power: applications and examples / _rWarren S. Browner, Thomas B. Newman, and Stephen B. Hulley -- _tDesigning a cohort study / _rSteven R. Cummings, Thomas B. Newman, and Stephen B. Hulley -- _tDesigning cross-sectional and case-control studies / _rThomas B. Newman [and others] -- _tEnhancing causal inference in observational studies / _rThomas B. Newman, Warren S. Browner, and Stephen B. Hulley
505	0	0	_tDesigning a randomized blinded trial / _rSteven R. Cummings, Deborah Grady, and Stephen B. Hulley -- _tAlternative trial designs and implementation issues / _rDeborah Grady, Steven R. Cummings, and Stephen B. Hulley -- _tDesigning studies of medical tests / _rThomas B. Newman [and others] -- _tUtilizing existing databases / _rDeborah Grady and Norman Hearst -- _tAddressing ethical issues / _rBernard Lo -- _tDesigning questionnaires and interviews / _rSteven R. Cummings and Stephen B. Hulley -- _tData management / _rMichael A. Kohn -- _tImplementing the study and quality control / _rDeborah Grady and Stephen B. Hulley -- _tCommunity and international studies / _rNorman Hearst and Thomas E. Novotny -- _tWriting and funding a research proposal / _rSteven R. Cummings and Stephen B. Hulley
520			_aProviding a practical guide to planning, tabulating, formulating, and implementing clinical research, with an easy-to-read, uncomplicated presentation. This edition incorporates current research methodology, including molecular and genetic clinical research, and offers an updated syllabus for conducting a clinical research workshop. Emphasis is on common sense as the main ingredient of good science. The book explains how to choose well-focused research questions and details the steps through all the elements of study design, data collection, quality assurance, and basic grant-writing. All chapters have been thoroughly revised, updated, and made more user-friendly
650		0	_aClinical trials
650		0	_aMedicine _xResearch _xMethodology
650		0	_aEpidemiology _xResearch _xMethodology
650	1	2	_aEpidemiologic Methods
650	2	2	_aResearch Design
650		2	_aClinical Trials as Topic
700	1		_aHulley, Stephen B
856			_yhttps://nhrc.gov.np/contact/
942			_2NLM _cBK
999			_c3415 _d3415