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003			OSt
005			20220906184552.0
008			190529b ||||| |||| 00| 0 eng d
060			_aTHS-00268
100			_aTimilsina, Ananta _aAdhikari, Bikash _aPariyar, Ramesh _aBaral, Samrat _aKoirala, Suraj _91914
245			_aA research report on phytochemical screening and evaluation of hair growth promoting activity of maharanga bicolor.
260			_cc2011.
300			_aviii, 33p. :
500			_aThesis Report.
520			_aABSTRACT: Alopecia is a dermatological disorder, in which a person loses hair to some or all extent. Plant derived medicines have been under investigation for hair growth promoting activity. Present study was conducted to perform phytochemical screening and to evaluate the hair growth promoting activity of Maharanga bicolor. Petroleum ether and ethanol extracts of rhizomes of Maharanga bicolor was compared with the standard Minoxidil treatment. Extracts in the concentration of 2% and 5% were prepared by incorporating in liquid paraffin and applied topically to the denuded skin of rats for 30 days. Minoxidil 2% solution was applied as positive control for comparison. The time in days required for hair growth initiation as well as completion was recorded. The length of hair was measured in 15th, 20th, 25th and 30th day of the application of the sample and was recorded. The result was interpreted as mean±S.D. At day 23 blind investigations was done to determine the hair growth among different rats. The results showed the hair initiation time of 2% petroleum ether was on 9th day and Minoxidil was on 8th day and that of control was on 12th day. The hair growth completion time was seen after 22nd day in 2% and 5% petroleum ether extract, after 20th day in Minoxidil and 27th day in control. Blind investigation reported the hair growth of the extracts were superior to control. Hair length of extracts was superior to the control and similar with the standard Minoxidil. The study provides a huge support to the traditional claim that M. bicolor acts as hair growth promoter. Both of the Petroleum ether and ethanol extract were found to potentiate the hair growth than control and similar to Minoxidil. Phytochemical screening of the petroleum ether and ethanol extracts of rhizomes Maharanga bicolor revealed the presence of glycosides, carbohydrates, fats and fixed oils, resins, phytosterols, phenols, diterpenes, proteins and amino acids. Key words: Maharanga bicolor, phytochemical screening, hair growth.
546			_aEng.
650			_aMaharanga bicolor. _92125
650			_aPhytochemical screening. _92126
650			_aHair growth. _92127
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942			_2NLM _cTR