A research proposal on health related quality of life and associated factors with medication adherence among tuberculosis patients in Gandaki province of Nepal.
ABSTRACT: Introduction: Tuberculosis is one of the most prevalent infectious diseases and a significant public health problem in Nepal as well as global. Health-related quality of life (HRQOL) provides a multidimensional perspective that encompasses a patient's physical, emotional, and social...
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| Language: | English |
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c2020.
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| 060 | |a THS-00575 | ||
| 100 | |a Yadav,Rajesh Kumar. |9 3780 | ||
| 245 | |a A research proposal on health related quality of life and associated factors with medication adherence among tuberculosis patients in Gandaki province of Nepal. | ||
| 260 | |c c2020. | ||
| 300 | |a xiii,98p. | ||
| 500 | |a Thesis Report. | ||
| 520 | |a ABSTRACT: Introduction: Tuberculosis is one of the most prevalent infectious diseases and a significant public health problem in Nepal as well as global. Health-related quality of life (HRQOL) provides a multidimensional perspective that encompasses a patient's physical, emotional, and social functioning. Poor adherence to the treatment regimen is a major cause of treatment failure and the emergence of drug resistance among TB patients. The emergences of resistance to anti-tuberculosis drugs have become a major public health problem in several countries and an obstacle to effective global TB control. Medication adherence is associated with the health-related quality of life of tuberculosis patients. Methods: This research was health facility based cross-sectional study and carried out among TB patients registered under DOTS and receiving treatment more than or equal to 60 days from health facilities of Gandaki province of Nepal. Structured interview schedule and validated questionnaires were used for data collection. Quality of life was assessed by using Nepali version of WHOQOL-BREF tools and Medication adherence was assessed by using Nepali version of Morisky medication adherence scale (MMSA-8) questionnaires. Data were entered in Epi-data software and analysis was performed with the help of the Statistical Package for Social Science (SPSS). The odds ratio with a 95% CI was calculated and a P-value of <0.05 was considered as cut off for statistical significance. Results: A total 180 TB patients were participated in this study. Overall quality of life of participants it was range from 10.75 to 89.25 with meanSD as 55.9614.65. The overall prevalence of medication adherence among tuberculosis participants was 79.4%. Participants who had experience of side effects of the TB medicine were associated with all domains except of psychological domain and overall HRQOL and co-infection TB participants were associated with all domains except of social relationship. Participants who haven't living with co-morbidities were more than four times more likely to adhere with medicine compared to participants who had living with co-morbidities. Conclusion: The supportive factors for quality of life and medication adherence among Tuberculosis patients were socio-economic factors (Hilly region, hindu religion, nuclear family, literate), life style related factors (not prior of alcohol consumption, not habit smokeless tobacco previously), diseases related factors (delay confirm TB diagnosis, Not experienced of side effects, aware about TB symptoms, haven't coinfection) and accessibility to health care facilities related factors (confirm TB diagnosis cost, favourable time for DOTS centre, health workers supervision during the medication, friendly relationship with health workers, know about the length of the treatment, TB status disclose). Key words: Quality of life, Medication Adherence, Tuberculosis, Gandaki Province, Nepal | ||
| 650 | |a Quality of life. |9 897 | ||
| 650 | |a Medication Adherence. |9 1061 | ||
| 650 | |a Tuberculosis, Gandaki Province. |9 3781 | ||
| 650 | |a Nepal. |9 362 | ||
| 856 | |u http://nhrc.gov.np/contact/ |y Visit NHRC Library | ||
| 942 | |2 NLM |c TR | ||