rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Pharamcotherapeutic management of hypertension in chronic kidney disease patients
  name:
    name part: Sapkota, Yunima.
    role:
      role term: creator
  type of resource: text
  origin info:
    date issued: c2021
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: print
    extent: 41p.
  abstract: ABSTRACT: Background: Hypertension (HTN) is a prominent co-morbidity being both a cause and a consequence of Chronic Kidney Disease (CKD). Often, blood pressure control has been a challenge in CKD patients and it has been found to worsen the clinical outcome leading to other cardiovascular (CV) effects. Methods: Cross-sectional descriptive study was carried out to study the pharmacotherapeutic management of HTN in CKD patients. CKD patients visiting the Nephrology outpatient department or receiving dialysis services and those who were prescribed antihypertensive drugs were included in the study. Inpatients were not included in the study due to the seriousness of comorbidities and CKD patients, diagnosed with HTN on the day of interview were also excluded from the study. Results: 119 CKD patients with hypertension were enrolled in the study. 43% patents belonged to the age group 41-60 years. Of them, 61% were males. Following the JNC- 8 Guidelines, only 30% of the patients met the target BP goal. Majority (36%) of the patients were prescribed dual therapy followed by mono therapy (27%), triple therapy (22%), combination of four (14%) and combination of five drugs (1%). The most commonly prescribed group of anti-hypertensive drugs for the treatment of hypertension in CKD patients were calcium Channel Blockers(79%), Loop Diuretics (47.9%), Alpha-1 Blocker (34.5%), Beta Blockers (30.3%0 , Alpha -2 Agoinst (17.6%), Angiotensin Receptor Blockers (8.4%), Alpha plus Beta Blockers (3.4%) and Angiotensin Converting Enzyme Inhibitors (0.8%). Only 4% of the total medicines were prescribed as Fixed-dose combinations (FDCs) and only 2.5% prescriptions were written in generic name. The median cost for antihypertensive treatment in a day was found to be NRs. 29. The cost was found higher in case of patients in uncontrolled BP group. Conclusion: Well management of hypertension can show down the progression of CKD and also prevent cardiovascular and cerebrovascular complications of h…
  note: Thesis Report.
  subject:
    topic: Pharamcotherapeutic
  subject:
    topic: Hypertension
  subject:
    topic: Chronic kidney disease
  classification: THS-00629
  identifier: http://nhrc.gov.np/contact/
  record info:
    record creation date: 220621
    record change date: 20220906184722.0