To study the frequency of dysplasia and carcinoma in cervical smears, their clinical presentation and their correlation with koilocytosis, presence of x-chromatin and their association with HSV - 2.
ABSTRACT: A total of 1,106 cases were studied during a one year period from 1/11/2056 to 30/10/2057. Majority of the lesions were Fast smears constituting 91.0%, Cervical intraepithelial neoplasia [CIN] and squamous cell carcinoma [SCC] cervix constituted 8.0 and 1.0% respectively. The percentage...
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| Language: | English |
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c2001.
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| LEADER | 02379 a2200253 4500 | ||
|---|---|---|---|
| 003 | OSt | ||
| 005 | 20220906184545.0 | ||
| 008 | 190515b ||||| |||| 00| 0 eng d | ||
| 952 | |0 0 |1 0 |2 NLM |4 0 |6 THS_00076_BAS_2001_000000000000000 |7 0 |9 549 |a NHRC |b NHRC |c REF |d 2012-07-15 |l 0 |o THS-00076/BAS/2001 |p THS-00076 |r 2012-07-15 |w 2012-07-15 |y TR | ||
| 999 | |c 543 |d 543 | ||
| 060 | |a THS-00076 | ||
| 100 | |a Bashyal, Reeta. |9 1676 | ||
| 245 | |a To study the frequency of dysplasia and carcinoma in cervical smears, their clinical presentation and their correlation with koilocytosis, presence of x-chromatin and their association with HSV - 2. | ||
| 260 | |c c2001. | ||
| 300 | |a 76p. : | ||
| 500 | |a Thesis Report. | ||
| 520 | |a ABSTRACT: A total of 1,106 cases were studied during a one year period from 1/11/2056 to 30/10/2057. Majority of the lesions were Fast smears constituting 91.0%, Cervical intraepithelial neoplasia [CIN] and squamous cell carcinoma [SCC] cervix constituted 8.0 and 1.0% respectively. The percentage of different grades of CIN being CIN I 85.0%, CIN I-II 5.0%, CIN II 4.0%, CIN II-III 2.0% and CIN III 4.0%. Thirty cases were taken as a study group. The commonest age group for CIN was 31-40 years 80.0% and for Carcinoma cervix above 50 years 63.0%. The most common risk factors were marriage before 20 years of age 80.00% and a low socioeconomic status 70.0%. The common presenting feature in CIN was pain lower abdomen 88.0% followed by whitish discharge per vagina and anorexia 60.0% each. Similarly in Carcinoma cervix pain lower abdomen 80.00% followed by weight loss 60.0% were the common presenting symptoms. Koilocytic change was seen in 41.0% of the cases of CIN I. The incidence of x-chromatin positivity gradually decreased is the lesion advanced, the p value between CIN I and CIN II (p=<0.02), CIN I and CIN III (p=0.00) and between CIN III and carcinoma cervix (p=<0.004) being significant. An association with HSV-2 was seen in 10.6% caes of CIN I, 33.3% cases of CIN III and 40.0% cases of Carvinoma cervix with a gradual rising antibody time of 1:2 in CIN I, 1:7 in CIN III and 1:7 to 1:9 in Carcinoma cervix respectively. | ||
| 546 | |a Eng. | ||
| 650 | |a Dysplasia. |9 1922 | ||
| 650 | |a Carcinoma. |9 1923 | ||
| 650 | |a Cervical Smears. |9 1924 | ||
| 650 | |a Koilocytosis. |9 1925 | ||
| 856 | |u http://nhrc.gov.np/contact/ |y Visit NHRC Library | ||
| 942 | |2 NLM |c TR | ||