Role of Serology, Neuroimaging and Stool Examination in Diagnosis of Neurocysticercosis

Background: Neurocysticercosis (NCC) is the infection of Central nervous system by the larval stage of Taenia solium (pork tapeworm). This tapeworm is a public health problem in most developing countries where pigs are raised and pork is consumed and where poverty, illiteracy and deficient sanitary...

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Main Authors:	Sapkota K, Dumre, SP, Karmacharya, K
Format:	Technical Report
Language:	en_US
Published:	2016
Subjects:	cases diagnosis Neurocysticercosis Neuroimaging serology
Online Access:	http://103.69.126.140:8080/handle/123456789/107
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spelling	oai:103.69.126.140:123456789-1072022-11-08T10:29:23Z Role of Serology, Neuroimaging and Stool Examination in Diagnosis of Neurocysticercosis Communicable/Infectious diseases Sapkota K Dumre, SP Karmacharya, K cases diagnosis Neurocysticercosis Neuroimaging serology Background: Neurocysticercosis (NCC) is the infection of Central nervous system by the larval stage of Taenia solium (pork tapeworm). This tapeworm is a public health problem in most developing countries where pigs are raised and pork is consumed and where poverty, illiteracy and deficient sanitary infrastructure are common. The main objective of this study is to find out the diagnostic significance of Serology and Neuroimaging and to detect intestinal carriers of the tapeworm. Methods: The design of the research is exploratory and descriptive and also analytical. It is based on qualitative questions, the laboratory data and imaging studies. The study site is Manipal Teaching Hospital (MTH), Pokhara. The patients of pediatric age group (age 1 to 15 years) who visit to the pediatric department either as an out-patient or in-patient are included in the study. During the study period from January 2008 to January 2010, a total of 200 samples of serum for serology and Stool for microscopy was collected and microbiologically processed. Results: Out of 200 samples of serum, 100 were from the cases with diagnosis of Neurocysticercosis. Pig rearing was seen in 26% of the cases. And 30% (8) of pig rearing children had harbor taenia species in intestine. The most commonly affected age group was 8-14 years. ELISA sensitivity, specificity, positive predictive value and negative predictive value were 87%, 84%, 84.7% and 86.6% respectively. Conclusions: Neurocysticercosis should be suspected in any cases with neurological symptoms (especially partial seizure) in Taenia endemic regions. Neuroimaging should be done in cases with clinically and epidemiologically suspected Neurocysticercosis to identify the type, location, nature/stages and number of intracranial lesions. Keywords: cases; diagnosis; Neurocysticercosis; Neuroimaging; serology. 2016-10-28T07:13:44Z 2022-11-08T10:10:21Z 2016-10-28T07:13:44Z 2022-11-08T10:10:21Z 2010 Technical Report http://103.69.126.140:8080/handle/123456789/107 en_US application/vnd.openxmlformats-officedocument.wordprocessingml.document
institution	My University
collection	DSpace
language	en_US
topic	cases diagnosis Neurocysticercosis Neuroimaging serology
spellingShingle	cases diagnosis Neurocysticercosis Neuroimaging serology Sapkota K Dumre, SP Karmacharya, K Role of Serology, Neuroimaging and Stool Examination in Diagnosis of Neurocysticercosis
description	Background: Neurocysticercosis (NCC) is the infection of Central nervous system by the larval stage of Taenia solium (pork tapeworm). This tapeworm is a public health problem in most developing countries where pigs are raised and pork is consumed and where poverty, illiteracy and deficient sanitary infrastructure are common. The main objective of this study is to find out the diagnostic significance of Serology and Neuroimaging and to detect intestinal carriers of the tapeworm. Methods: The design of the research is exploratory and descriptive and also analytical. It is based on qualitative questions, the laboratory data and imaging studies. The study site is Manipal Teaching Hospital (MTH), Pokhara. The patients of pediatric age group (age 1 to 15 years) who visit to the pediatric department either as an out-patient or in-patient are included in the study. During the study period from January 2008 to January 2010, a total of 200 samples of serum for serology and Stool for microscopy was collected and microbiologically processed. Results: Out of 200 samples of serum, 100 were from the cases with diagnosis of Neurocysticercosis. Pig rearing was seen in 26% of the cases. And 30% (8) of pig rearing children had harbor taenia species in intestine. The most commonly affected age group was 8-14 years. ELISA sensitivity, specificity, positive predictive value and negative predictive value were 87%, 84%, 84.7% and 86.6% respectively. Conclusions: Neurocysticercosis should be suspected in any cases with neurological symptoms (especially partial seizure) in Taenia endemic regions. Neuroimaging should be done in cases with clinically and epidemiologically suspected Neurocysticercosis to identify the type, location, nature/stages and number of intracranial lesions. Keywords: cases; diagnosis; Neurocysticercosis; Neuroimaging; serology.
format	Technical Report
author	Sapkota K Dumre, SP Karmacharya, K
author_facet	Sapkota K Dumre, SP Karmacharya, K
author_sort	Sapkota K
title	Role of Serology, Neuroimaging and Stool Examination in Diagnosis of Neurocysticercosis
title_short	Role of Serology, Neuroimaging and Stool Examination in Diagnosis of Neurocysticercosis
title_full	Role of Serology, Neuroimaging and Stool Examination in Diagnosis of Neurocysticercosis
title_fullStr	Role of Serology, Neuroimaging and Stool Examination in Diagnosis of Neurocysticercosis
title_full_unstemmed	Role of Serology, Neuroimaging and Stool Examination in Diagnosis of Neurocysticercosis
title_sort	role of serology, neuroimaging and stool examination in diagnosis of neurocysticercosis
publishDate	2016
url	http://103.69.126.140:8080/handle/123456789/107
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Role of Serology, Neuroimaging and Stool Examination in Diagnosis of Neurocysticercosis

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