Progesterone for Prevention of Recurrent Preterm Labor after Threatened Preterm Labor - A Randomized Controlled Trial

Background: Preterm birth is the major cause of neonatal mortality and morbidity. In addition, prematurity is strongly associated with long-term developmental disabilities, accounting for 1 in 5 children with mental retardation, 1 in 3 children with vision impairment, and almost half of children wit...

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Main Author:	Uprety, D
Format:	Technical Report
Language:	en_US
Published:	2016
Subjects:	preterm labor progesterone tocolysis
Online Access:	http://103.69.126.140:8080/handle/123456789/221
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spelling	oai:103.69.126.140:123456789-2212022-11-08T10:29:30Z Progesterone for Prevention of Recurrent Preterm Labor after Threatened Preterm Labor - A Randomized Controlled Trial Reproductive Health Uprety, D preterm labor progesterone tocolysis Background: Preterm birth is the major cause of neonatal mortality and morbidity. In addition, prematurity is strongly associated with long-term developmental disabilities, accounting for 1 in 5 children with mental retardation, 1 in 3 children with vision impairment, and almost half of children with cerebral palsy. So, prevention of preterm birth is a public health priority. Methods: A randomized controlled trial was undertaken in BP Koirala Institute of Health Sciences, where 60 patients were randomized into group 1 (n=29, weekly intramuscular Progesterone) and group 2 (n=31, no treatment) after the arrest of preterm labor with tocolysis. Their latency period till delivery and recurrence of preterm labor and neonatal outcomes were compared Results: There was significant reduction in recurrence of preterm labor and increase in latency period in progesterone group. However neonatal outcomes were similar. Conclusions: Progesterone is useful in reducing the recurrence of preterm labor in a patient who had preterm labor. Keywords: preterm labor; progesterone; tocolysis. 2016-10-26T07:10:40Z 2022-11-08T10:11:17Z 2016-10-26T07:10:40Z 2022-11-08T10:11:17Z 2010 Technical Report http://103.69.126.140:8080/handle/123456789/221 en_US application/vnd.openxmlformats-officedocument.wordprocessingml.document
institution	My University
collection	DSpace
language	en_US
topic	preterm labor progesterone tocolysis
spellingShingle	preterm labor progesterone tocolysis Uprety, D Progesterone for Prevention of Recurrent Preterm Labor after Threatened Preterm Labor - A Randomized Controlled Trial
description	Background: Preterm birth is the major cause of neonatal mortality and morbidity. In addition, prematurity is strongly associated with long-term developmental disabilities, accounting for 1 in 5 children with mental retardation, 1 in 3 children with vision impairment, and almost half of children with cerebral palsy. So, prevention of preterm birth is a public health priority. Methods: A randomized controlled trial was undertaken in BP Koirala Institute of Health Sciences, where 60 patients were randomized into group 1 (n=29, weekly intramuscular Progesterone) and group 2 (n=31, no treatment) after the arrest of preterm labor with tocolysis. Their latency period till delivery and recurrence of preterm labor and neonatal outcomes were compared Results: There was significant reduction in recurrence of preterm labor and increase in latency period in progesterone group. However neonatal outcomes were similar. Conclusions: Progesterone is useful in reducing the recurrence of preterm labor in a patient who had preterm labor. Keywords: preterm labor; progesterone; tocolysis.
format	Technical Report
author	Uprety, D
author_facet	Uprety, D
author_sort	Uprety, D
title	Progesterone for Prevention of Recurrent Preterm Labor after Threatened Preterm Labor - A Randomized Controlled Trial
title_short	Progesterone for Prevention of Recurrent Preterm Labor after Threatened Preterm Labor - A Randomized Controlled Trial
title_full	Progesterone for Prevention of Recurrent Preterm Labor after Threatened Preterm Labor - A Randomized Controlled Trial
title_fullStr	Progesterone for Prevention of Recurrent Preterm Labor after Threatened Preterm Labor - A Randomized Controlled Trial
title_full_unstemmed	Progesterone for Prevention of Recurrent Preterm Labor after Threatened Preterm Labor - A Randomized Controlled Trial
title_sort	progesterone for prevention of recurrent preterm labor after threatened preterm labor - a randomized controlled trial
publishDate	2016
url	http://103.69.126.140:8080/handle/123456789/221
work_keys_str_mv	AT upretyd progesteroneforpreventionofrecurrentpretermlaborafterthreatenedpretermlaborarandomizedcontrolledtrial AT upretyd reproductivehealth
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Progesterone for Prevention of Recurrent Preterm Labor after Threatened Preterm Labor - A Randomized Controlled Trial

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