Progesterone for prevention of recurrent preterm labor after threatened preterm labor -A randomized controlled trial

Introduction Preterm birth is the major cause of neonatal mortality and morbidity. In addition, prematurity is strongly associated with long-term developmental disabilities, accounting for 1 in 5 children with mental retardation, 1 in 3 children with vision impairment, and almost half of children w...

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Main Author:	Uprety, Prof. Dr. Dhruba
Format:	Technical Report
Language:	en_US
Published:	2012
Subjects:	Progesterone Tocolysis Preterm labor
Online Access:	http://103.69.126.140:8080/handle/123456789/693
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spelling	oai:103.69.126.140:123456789-6932022-11-09T06:29:20Z Progesterone for prevention of recurrent preterm labor after threatened preterm labor -A randomized controlled trial Uprety, Prof. Dr. Dhruba Progesterone Tocolysis Preterm labor Introduction Preterm birth is the major cause of neonatal mortality and morbidity. In addition, prematurity is strongly associated with long-term developmental disabilities, accounting for 1 in 5 children with mental retardation, 1 in 3 children with vision impairment, and almost half of children with cerebral palsy. So, prevention of preterm birth is a public health priority. Methods A randomized controlled trial was undertaken in BP Koirala Institute of Health Sciences, where 60 patients were randomized into group 1 (n=29, weekly intramuscular Progesterone) and group 2 ( n=31,no treatment) after the arrest of preterm labor with tocolysis. Their latency period till delivery and recurrence of preterm labor and neonatal outcomes were compared. Results There was significant reduction in recurrence of preterm labor and increase in latency period in progesterone group. However neonatal outcomes were similar. Conclusion Progesterone is useful in reducing the recurrence of preterm labor in a patient who had preterm labor. 2012-12-28T05:24:40Z 2022-11-08T10:18:28Z 2012-12-28T05:24:40Z 2022-11-08T10:18:28Z 2012-12-27 Technical Report http://103.69.126.140:8080/handle/123456789/693 en_US application/pdf
institution	My University
collection	DSpace
language	en_US
topic	Progesterone Tocolysis Preterm labor
spellingShingle	Progesterone Tocolysis Preterm labor Uprety, Prof. Dr. Dhruba Progesterone for prevention of recurrent preterm labor after threatened preterm labor -A randomized controlled trial
description	Introduction Preterm birth is the major cause of neonatal mortality and morbidity. In addition, prematurity is strongly associated with long-term developmental disabilities, accounting for 1 in 5 children with mental retardation, 1 in 3 children with vision impairment, and almost half of children with cerebral palsy. So, prevention of preterm birth is a public health priority. Methods A randomized controlled trial was undertaken in BP Koirala Institute of Health Sciences, where 60 patients were randomized into group 1 (n=29, weekly intramuscular Progesterone) and group 2 ( n=31,no treatment) after the arrest of preterm labor with tocolysis. Their latency period till delivery and recurrence of preterm labor and neonatal outcomes were compared. Results There was significant reduction in recurrence of preterm labor and increase in latency period in progesterone group. However neonatal outcomes were similar. Conclusion Progesterone is useful in reducing the recurrence of preterm labor in a patient who had preterm labor.
format	Technical Report
author	Uprety, Prof. Dr. Dhruba
author_facet	Uprety, Prof. Dr. Dhruba
author_sort	Uprety, Prof. Dr. Dhruba
title	Progesterone for prevention of recurrent preterm labor after threatened preterm labor -A randomized controlled trial
title_short	Progesterone for prevention of recurrent preterm labor after threatened preterm labor -A randomized controlled trial
title_full	Progesterone for prevention of recurrent preterm labor after threatened preterm labor -A randomized controlled trial
title_fullStr	Progesterone for prevention of recurrent preterm labor after threatened preterm labor -A randomized controlled trial
title_full_unstemmed	Progesterone for prevention of recurrent preterm labor after threatened preterm labor -A randomized controlled trial
title_sort	progesterone for prevention of recurrent preterm labor after threatened preterm labor -a randomized controlled trial
publishDate	2012
url	http://103.69.126.140:8080/handle/123456789/693
work_keys_str_mv	AT upretyprofdrdhruba progesteroneforpreventionofrecurrentpretermlaborafterthreatenedpretermlaborarandomizedcontrolledtrial
_version_	1761501156806230016

Progesterone for prevention of recurrent preterm labor after threatened preterm labor -A randomized controlled trial

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