Extended spectrum beta-lactamase producing klebsiella pneumoniae isolated from urinary tract infected patients. (Record no. 2324)
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| fixed length control field | 02805nam a22002297a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20230818124253.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 160328b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Description conventions | NLM |
| 050 ## - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | THS-00406 |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Chaudhary, Prakash. |
| 9 (RLIN) | 3823 |
| 245 ## - TITLE STATEMENT | |
| Title | Extended spectrum beta-lactamase producing klebsiella pneumoniae isolated from urinary tract infected patients. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | c2015. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | xiii, 57p. |
| 500 ## - GENERAL NOTE | |
| General note | Thesis Report. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | ABSTRACT: Klebsiella pneumoniae, one of the bacterial agents associated with urinary tract infection has been often implicated as a major extended spectrum beta-lactamase (ESBL) producer in last few decades. This study was designed to assess the prevalence of ESBL producing klebsiella pneumoniae in urinary isolates at a tertiary care hospital in Kathmandu, Nepal,from July 2014 to December 2014. One thousand nine hundred eighty six mid-stream urine specimens were collected aseptically from the clinically suspected patients of urinary tract infections attending Capital hospital and research center, Kathmandu. The samples were processed following standard guidelines as recommended by American Society for Microbiology (ASM) and the isolates including Klebsiella spp. were identified using the specific biochemical and sugar fermentation tests recommended by ASM. Antibiotic sensitivity testing was done by modified Kirby-Bauer disk diffusion method and interpreted following Clinical and Laboratory Standards Institute (CLSI) guidelines. klebsiella pneumoniae isolates showing resistance upon initial screening with ceftriaxone (30µg) disc were then confirmed for ESBL production by phenotypic confirmatory disc diffusion test (PCDDT) using ceftazidime (30µg) and ceftazidime+ clavulanic acid (30µg+10µg) and cefotaxime (30µg) and cefotaxime+clavulanic acid (30µg+10µg) disc as per CLSI guidelines. Out of a total 1986 specimens investigated, Escherichia coli was isolated in 309(83.9%) and Klebsiella pneumoniae in 38 (10.3%) cases. Initial screening with ceftriaxone disc revealed 18 isolates of Klebsiella pneumoniae to be resistant. Further testing by PCDDT method confirmed 7 (18.4%) Klebsiella pneumoniae isolates to be ESBL producers. Compared to some earlier studies done in Nepal, higher prevalence of ESBL-producing Klebsiella pneumoniae was observed warranting a national surveillance for routine monitoring of ESBL producing Klebsiella pneumoniae isolates. Keywords: Extended spectrum beta lactamase (ESBL), Klebsiella pneumoniae, Urinary Tract Infection (UTI) |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Extended spectrum beta lactamase (ESBL). |
| 9 (RLIN) | 3824 |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Klebsiella pneumoniae. |
| 9 (RLIN) | 3825 |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Urinary tract infection (UTI). |
| 9 (RLIN) | 3826 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://nhrc.gov.np/contact/">http://nhrc.gov.np/contact/</a> |
| Link text | Visit NHRC Library |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | National Library of Medicine |
| Koha item type | Thesis Report |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Date acquired | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| National Library of Medicine | Nepal Health Research Council | Nepal Health Research Council | 03/28/2016 | THS00406/CHA/2015 | THS-00406 | 03/28/2016 | 03/28/2016 | Thesis Report |