Pulmonary arterial compliance in children with atrial and ventricular septal defect. (Record no. 2334)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03393nam a22002657a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20230818122702.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 160719b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Description conventions | NLM |
| 060 ## - NATIONAL LIBRARY OF MEDICINE CALL NUMBER | |
| Classification number | THS-00414 |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Basnet, Narayan Bahadur. |
| 9 (RLIN) | 3880 |
| 245 ## - TITLE STATEMENT | |
| Title | Pulmonary arterial compliance in children with atrial and ventricular septal defect. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | c2000. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 55p. |
| 500 ## - GENERAL NOTE | |
| General note | Thesis Report. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Abstract: <br/><br/>Background: previous studies have documented the normal values of pulmonary arterial compliance (Cp) in animals and adult human beings. However, a limited number of such studies have been performed in patients with cardiac septal defects. The objectives of this study were to determine the normal reference value of Cp in children and its changes in atrial septal defects (ASD), ventricular septal defects (VSD) and ventricular septal defects with pulmonary hypertension (VSDPH) by utilizing pulmonary arterial resistance (Rp) and pulmonary arterial time constant (Tp). <br/><br/>Methods: Cp was calculated based on the pulmonary arterial diastolic pressure waveform minus the left atrial pressure difference as an exponential function of time. First, Cp was estimated by studying the main pulmonary artererial pressure (MPAP) waveform obtained from both routine cardiac catheterization and the pressure measured by a cather-tip-manometer, which was performed during the catheterization study of 7 children with various congenital heart diseases. Secondly, 124 children with attial and ventricular septal defects between 45 days and 12 years of age were studied using the data obtained from the routine catheterization. Hemodynamic data were utilized to calculate the Rp, Tp and Cp. <br/><br/> Results: A strong correlation (r=0.954) was found in the Cp value estimated by data obtained from the routine catheterization and from the catheter-tip manometer study. A strong relationship (r=0.879) between the Cp estimated by previous method and the new method was also found. This study showed an estimated normal children's mea (SEM) Cp at 1053 (0.17) ml mm Hg-1m-2. The estimated Cp was 1.91 (0.10) and 1.70 (0.11) in ASD and VSD patients, respectively. It was found that Cp was significantly (p=0.004) higher in female patients with a VSD. Also, a significantly low Cp, 0.95 (0.06) ml mm Hg-1 m-2, was observed in patients with a VSDPH. In 3 patients with VSDPH associated with physiologically insignificant minor anomalies, Cp changed from a low value to normal range (1.18-1.88 ml mm Hg-1m-2) after surgical repair of VSD. <br/><br/>Conclusion: A normal Cp value was estimated in children. A significantly low Cp was observed in patients with a VSDPH indicating low expansibility. Cp was higher in females than males in VSD patients. MPAP wave from obtained from routine cardiac catheterization can be utilized to estimate the Cp in children with atrial and ventricular septal defect. Cp may be useful for the early recognition of the pulmonary hypertension in postoperative patients with septal defects. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Congenital Heart Disease. |
| 9 (RLIN) | 3881 |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pediatrics. |
| 9 (RLIN) | 3882 |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pulmonary Arterial Compliance. |
| 9 (RLIN) | 3883 |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pulmonary Artery. |
| 9 (RLIN) | 3884 |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pulmonary Hypertension. |
| 9 (RLIN) | 3885 |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Septal Defects. |
| 9 (RLIN) | 3886 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://nhrc.gov.np/contact/">http://nhrc.gov.np/contact/</a> |
| Link text | Visit NHRC Library |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | National Library of Medicine |
| Koha item type | Thesis Report |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Date acquired | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| National Library of Medicine | Nepal Health Research Council | Nepal Health Research Council | 07/19/2016 | THS00414/BAS/2000 | THS-00414 | 07/19/2016 | 07/19/2016 | Thesis Report |