Molecular characterization of extended spectrum beta lactamase producing bacterial strains isolated from diarrheal patients. (Record no. 2567)
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| 000 -LEADER | |
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| fixed length control field | 02915nam a22002537a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220906184702.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 181204b ||||| |||| 00| 0 eng d |
| 060 ## - NATIONAL LIBRARY OF MEDICINE CALL NUMBER | |
| Classification number | THS00466 |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Neupane,Bibhusan . |
| 9 (RLIN) | 1166 |
| 245 ## - TITLE STATEMENT | |
| Title | Molecular characterization of extended spectrum beta lactamase producing bacterial strains isolated from diarrheal patients. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | c2016. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | xiv,61p. |
| 500 ## - GENERAL NOTE | |
| General note | Thesis Report. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | ABSTRACT: Infectious diarrheal diseases are responsible for considerable morbidity and mortality especially in developing countries. Multidrug resistant organism and extended spectrum beta lactamase producing organism are growing problem in the treatment of infections. So the present study was carried out to detect the multidrug resistant organism and Extended spectrum beta lactamase producing organism isolated from patients suffering from diarrhea and visited Sukrraj Tropical and Infectious Disease. Hospital for treatment from mid-June 2014 to mid-December 2014. 624 stool specimens were collected from patients and cultured by standard microbiological technique. Isolated bacteria were identified by biochemical test and serotyping. These bacterial strains were subjected for Antibiotic susceptibility testing following Kirby Bauer disk diffusion technique as per CLSI guideline. ESBL producing strains were screened by disk diffusion and disk combination method. Phenotypic detected ESBL producing organisms were subjected for molecular characterization. Among culture positivity of stool culture, Vibrio cholera, salmonella and Shigella species were detected . 31 were Shigella species among them 17 were Shigella flexneri, 8 were Shigella sonnei, and 2 were Shigella dysenteriae, I was Shigella boydii and 3 were Shigella species which were biochemically confirmed, 22 were Vibrio cholera and 7 were Salmonella enteric serovar Typhimurium. Most Shigella were resistant to antibiotic, most of them were highly resistant to Nalixidic Acid, Ciprofloxacin, Ampicillin and Cotrimoxazole while more resistant to Vibrio Cholerae but Cefotaxime, Tetracycline and Ciprofloxacinwere more susceptible. One isolates among Salmonella enteric serovar Typhimurium was multidrug resistant while other were susceptible to antibiotics. One isolates each from Shigella flexneri, Vibrio cholera and Salmonella enteric serovar Typhimurium were ESBL producerin phenotypic detection. Vibrio Cholerae and Salmonella enteric serovar Typhimurium possess CTX-M gene indicating the threats of ESBL producing bacteria. Key Words: AST, CTX, Diarrhea, Vibrio Cholerae, Shigella , Salmonella |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | AST. |
| 9 (RLIN) | 1167 |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | CTX. |
| 9 (RLIN) | 1168 |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Diarrhea. |
| 9 (RLIN) | 965 |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Vibrio Cholerae. |
| 9 (RLIN) | 330 |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Shigella. |
| 9 (RLIN) | 1169 |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Salmonella. |
| 9 (RLIN) | 1170 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://nhrc.gov.np/contact/">http://nhrc.gov.np/contact/</a> |
| Link text | Visit NHRC Library |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | National Library of Medicine |
| Koha item type | Thesis Report |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Date acquired | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| National Library of Medicine | Nepal Health Research Council | Nepal Health Research Council | 12/04/2018 | THS00466/NEU/2016 | THS-00466 | 12/04/2018 | 12/04/2018 | Thesis Report |