Clinical profile and outcome of patients with acute exacerbation of COPD presenting to tertiary care center of Nepal. (Record no. 3179)
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| 000 -LEADER | |
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| fixed length control field | 02979nam a22002297a 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20230403113020.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 230403b |||||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Description conventions | NLM |
| 060 ## - NATIONAL LIBRARY OF MEDICINE CALL NUMBER | |
| Classification number | THS-00680 |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Upadhyay, Devansh. |
| 245 ## - TITLE STATEMENT | |
| Title | Clinical profile and outcome of patients with acute exacerbation of COPD presenting to tertiary care center of Nepal. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | c2022. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 19p. |
| 500 ## - GENERAL NOTE | |
| General note | Thesis Report. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | ABSTRACT:<br/><br/>Background: Chronic Obstructive Pulmonary Disease (COPD) is characterized by persistent respiratory symptoms and airflow limitation that is due to airway and /or alveolar abnormalities usually influenced by several host and environmental factors. Dyspnea, cough, sputum production, history of recurrent lower respiratory tract infections are presenting symptoms that are often under-reported by patients. An exacerbation of COPD is a sustained worsening of the patient's condition, from the stable state and beyond normal day-to-day variations that is acute in onset and may warrant additional treatment in a patient with underlying COPD. This study aims to describe clinical profile and short-term outcome of patients admitted with acute exacerbation of COPD diagnosed either clinically only or with GOLD criteria in a tertiary care hospital. <br/><br/>Methodology: A descriptive observational study based on questionnaire and hospital records was carried out in Department of Pulmonology and Critical Care Medicine, TUTH for a period of five months from 9th December 2021 to 8th May, 2022. The study population consisted of consecutive patients admitted to the department for at least one day within the time frame with diagnosis of acute exacerbation of COPD. <br/><br/>Results: There were 30 patients, predominantly female (60%) from rural Nepal (80%) with median age of 71 years, mostly smokers (66.67%) and significant firewood smoke exposure (80%), living with COPD for median duration of 7 years [range 1-30 years] and all categorized into group D in GOLD A-D classification. There was a low prevalence of spirometry use to diagnose COPD. ABG, chest x-rays and ECG were performed in all the patients. Antibiotics, short-acting beta agonists, long acting beta agonists and inhaled and systemic corticosteroids were prescribed in majority of the patients based on GOLD guidelines. Substantial proportion (63.33%) had cor pulmonale as well and were under diuretics.<br/><br/> Conclusion: A variety of host factors and environmental factor affects the natural course of COPD once diagnosed. The exacerbations accelerates the damage that the lung sustains and invites more severe and frequent exacerbations and hospitalizations. Cessation of smoking and avoiding exposure to firewood smoke and timely medical consults during the exacerbations are recommended. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Clinical profile. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Exacerbation. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | COPD. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Nepal. |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Link text | http://www.nhrc.gov.np/ |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | National Library of Medicine |
| Koha item type | Thesis Report |
| Suppress in OPAC | No |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Date acquired | Inventory number | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| National Library of Medicine | Nepal Health Research Council | Nepal Health Research Council | 04/03/2023 | 680 | THS00680/UPA/2022 | 00680 | 04/03/2023 | 04/03/2023 | Thesis Report |