Serum calcium phosphate product as a predictor of mortality in hospitalized patients. (Record no. 3301)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02046nam a22002297a 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20230728123542.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 230728b |||||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Description conventions | NLM |
| 060 ## - NATIONAL LIBRARY OF MEDICINE CALL NUMBER | |
| Classification number | THS-00723 |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Bhattarai,Abhinav. |
| 245 ## - TITLE STATEMENT | |
| Title | Serum calcium phosphate product as a predictor of mortality in hospitalized patients. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | c2023. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 74p. |
| 500 ## - GENERAL NOTE | |
| General note | Thesis Report. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | ABSTRACT:<br/><br/>Background and aim: Recent studies have shown that elevated calcium phosphate arithmetic product (CaP) can lead to <br/>extraosseous calcifications and increase the risk of death. The aim of this study was to compare <br/>the admission CaP between survivors and non survivors and investigate if that could predict the <br/>survival outcomes in critically ill non-CKD patients. <br/><br/>Methods: Altogether 126 study participants were enrolled which comprised of 3 cohorts: 52 critically ill non<br/>CKD patients, 49 CKD patients and 25 healthy subjects. Blood samples were collected within 24 <br/>hours of admission and calcium, phosphate, and CaP were estimated. Statistical analysis was <br/>performed on SPSS version 25. <br/><br/>Results: The admission levels of phosphate, and CaP were significantly higher in non-survivors (p= 0.002 <br/>and 0.011). Regression analysis revealed that phosphate (r2=0.170, p= 0.002) and CaP (r2=0.122, <br/>p= 0.011) could significantly predict mortality. ROC analysis showed satisfactory performance of <br/>admission phosphate and CaP (AUC= 0.719 and 0.621) in classifying patients at risk of mortality. <br/>Kaplan-Meier survival analysis showed the lowest survival rates in admission CaP < 22 mg2/dL2 <br/>and > 43 mg2/dL2. <br/><br/>Conclusion: Abnormal CaP is associated with increased incidence of mortality in critically ill patients and <br/>measuring CaP at admission can be a useful tool to predict the survival outcomes. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Serum. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Calcium phosphate. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Predictor of mortality. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Hospitalized patients. |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Link text | https://www.nhrc.gov.np/ |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | National Library of Medicine |
| Koha item type | Thesis Report |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Inventory number | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| National Library of Medicine | Nepal Health Research Council | Nepal Health Research Council | Reference | 07/28/2023 | 723 | THS00723/BHA/2023 | THS-00723 | 07/28/2023 | 07/28/2023 | Thesis Report |