Study of clinical and Biochemical profiles and closed needle pleural biopsy findings in patients with exudative pleural effusion. (Record no. 463)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 04056 a2200241 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220906184542.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190123b ||||| |||| 00| 0 eng d |
| 060 ## - NATIONAL LIBRARY OF MEDICINE CALL NUMBER | |
| Classification number | THS00019 |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Shrestha, Sudip. |
| 9 (RLIN) | 1597 |
| 245 ## - TITLE STATEMENT | |
| Title | Study of clinical and Biochemical profiles and closed needle pleural biopsy findings in patients with exudative pleural effusion. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | c1998. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | xxxii, 86p. |
| 500 ## - GENERAL NOTE | |
| General note | Thesis Report. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | ABSTRACT: Exudative pleural effusion is a common presentation of different intrathoracic or extrathoracic etiology. The purpose of this cross-sectional descriptive study were: i. to find out the pleural biopsy histopathology in patients with exudative pleural effusion, ii. to compare the clinical profiles in different etiological groups of the patients presenting with exudative pleural effusion and iii. to compare the biochemical profile (sugar, protein, LDH) in different etiological groups of the patients presenting with exudative pleural effusion. 40 consecutive subjects of exudative pleural effusion attending the outpatient department and indoor patient of the Department of Medicine of TUTH and Bir Hospital in the period of July 1997 to April 1998 were studied. Two patients were excluded from the study. After taking history and through physical examination the chest x-ray posterior-anterior view diagnostici pleural tapping done. Serum protein, sugar and LDH were estimated. The patients were subjected to pleural biopsy by using Abrams pleural biopsy needle. The histological findings are grouped into following headings: (a). Granulomatous, (b). Neoplastic, (c). Non specific, and (d). Normal. The mean age of the study group was 42 years (SD= 20.6). Male were more than female (Male=68.4%). Histologic finding of the pleural biopsy were: granulomatous 42.1%, neoplastic 13.2% while 44.7% were found to be non specific inflammation. The pleural biopsy was most useful in the diagnosis of tubercular pleural effusion followed by malignant pleural effusion. The clinical profiles of the three different histopathological groups had been compared and found that there was no significant different in age, sex and duration of symptoms. The symptoms like anorexia and weight loss, respiratory symptoms like cough dyspnea, chest pain were common in all. Fever was less common in neoplastic group and more common in tubercular and nonspecific group, which was statically significant. It was also found that, the emaciated, pale and ill looking patients were more often due to malignant pleural effusion. Pleural biopsy was more often diagnostic in such situation. Radiological massive pleural effusion occupying whole hemthorax was more often malignant. Pleural biopsy has high success rate to diagnose such effusion. The study of pleural fluid revealed that the serosanguinous and bloody pleural effusion in tuberculosis was rare. They were commonly straw colour: Frankly haemorrhagic effusion in the absence of trauma was commonly due to malignancy. None of the group revealed any significant difference in serum and pleural fluid ratio of sugar. LDH and protein. But when considering the parameter(sugar. LDH and protein.) individually. in granulomatous effusion (tubercular) always had sugar level > 3.33 mmol /L. Malignant pleural effusion almost always had LDH > 200 IU. The result also concluded that pleural fluid protein level through raised more than 3 gm/L most of the time not useful for etiological diagnosis in exudaative effusions. The procedure was simple and safe with minimal complication. The diagnostic vield was in the tune of 52%. Being simple and safe procedure with good diagnostic vield it should be a part of the initial investigation of every patient with pleural effusion of uncertain aetiologies. |
| 546 ## - LANGUAGE NOTE | |
| Language note | Eng. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Clinical. |
| 9 (RLIN) | 1619 |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Biochemical. |
| 9 (RLIN) | 1620 |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pleural Biopsy. |
| 9 (RLIN) | 1621 |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pleural Effusion. |
| 9 (RLIN) | 1622 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://nhrc.gov.np/contact/">http://nhrc.gov.np/contact/</a> |
| Link text | Visit NHRC Library |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | National Library of Medicine |
| Koha item type | Thesis Report |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| National Library of Medicine | Nepal Health Research Council | Nepal Health Research Council | Reference | 07/11/2012 | THS-00019/SHR/1998 | THS-00019 | 07/11/2012 | 07/11/2012 | Thesis Report |