Aetiological incidenceof obstructive jaundice androle of endoscopic retrograde cholangiopancreatography in it's evaluation and therapy in nepalese set up. (Record no. 515)

MARC details
000 -LEADER
fixed length control field 03498 a2200229 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220906184544.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 190211b ||||| |||| 00| 0 eng d
060 ## - NATIONAL LIBRARY OF MEDICINE CALL NUMBER
Classification number THS-00060
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Adhikari, Shital.
9 (RLIN) 1648
245 ## - TITLE STATEMENT
Title Aetiological incidenceof obstructive jaundice androle of endoscopic retrograde cholangiopancreatography in it's evaluation and therapy in nepalese set up.
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Date of publication, distribution, etc. c2001.
300 ## - PHYSICAL DESCRIPTION
Extent ii, 90p.
500 ## - GENERAL NOTE
General note Thesis Report.
520 ## - SUMMARY, ETC.
Summary, etc. ABSTRACT: 1. Objectives: 1. To determine the aetiological incidence of the obstructive jaundice in our centres. 2. To assess the role of Endoscopic Retrograde Cholangiopancreatography in its evaluation and therapy in our set up. 2. Design: Prospective cross-sectional descriptive study of 50 consecutive patients of obstructive jaundice 3. Setting: Patients with obstructive jaundice admitted in Bir and Kathmandu hospitals. 4.Subjects: Patients with features of cholestasis with or without cholangitis and cholestatic picture on liver function tests and ultrasound showing common blie duct diameter > 8mm were included in the study. 5. Observations: Out of 50 patients included in the study, 40% were male and 60% female; the commonest age group was 61-70 years. Most of the patients presented with multiple complaints but almost all (92%), vomiting 960%), weight loss (48%) and right hypochondriac pain (40%) were the other complaints. 16% patients (all with malignant cause) had ascites at presentation and 4% had metastatic deposit at left supraclavicular lymph node. 80% patients had prolonged PT (difference > 4sec) but it was correctable in 96% of cases with vitamin K1. With endoscopic retrograde cholangiopancreatography, visualization of the biliary and pancreatic tree (when indicated) was acjoeved om 97.5% cases and diagnosis was established correctly in 98% cases. Removal of common bile duct stome by endoscopic sphincterotmy was successful in 77.77% case, stenting for malignant biliary stricture in 66.66% and removing parasites obstructing the common bile duct in 100%. Mortality was only 2% and hospital stay was significantly less (1.74+-1.84 versus 15.666+-3.65 days) when compared with the mean hospital stay of patients undergoing surgical procedure (p=0.0035). The commonest cause of obstructive jaundice in our centres was choledocholithiasis (48%) followed by carcinoma of the head of pancreas (14%) and carcinoma of the gallbladder (12%). Parasites (3%), post-operative biliary stricture 93%) and cholangiocarcinoma (2%) were less frequent causes. 6. Conclusion: Choledocholithiasis was the commonest cause of obstructive jaundice (48%) with female predominance followed by carcinoma of the head of pancreas (14%) with male predominance and carcinoma of the gallbladder (12%) with male to female ratio of 1:5. Visualisation of pancreaticobiliary tree was achieved in 97.5% cases by endoscopic retrograde cholangiopanereatography and diagnosis was established correctly in 98% cases. The therapeutic success was 77.77% in common bile duct stone removal, 66.66% in stenting the duct in malignant stricture and 100% in removing parasites obstructing the common bile duct. Mortality was low only 2% and hospital stay was significantly less.
546 ## - LANGUAGE NOTE
Language note Eng.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Aetiologicalincidence.
9 (RLIN) 1738
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Jaundice.
9 (RLIN) 1739
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cholangiopancreatography.
9 (RLIN) 1740
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://nhrc.gov.np/contact/">http://nhrc.gov.np/contact/</a>
Link text Visit NHRC Library
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme National Library of Medicine
Koha item type Thesis Report
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
    National Library of Medicine     Nepal Health Research Council Nepal Health Research Council Reference 07/12/2012   THS-00060/ADH/2001 THS-00060 07/12/2012 07/12/2012 Thesis Report

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