Sero-epidemiology of dengue virus infection in Western Terai Region of Nepal (Record no. 705)

MARC details
000 -LEADER
fixed length control field 02866 a2200253 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20230918115409.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 191115b ||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Description conventions NLM
060 ## - NATIONAL LIBRARY OF MEDICINE CALL NUMBER
Classification number THS-00234
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Shah, Yogendra.
9 (RLIN) 1881
245 ## - TITLE STATEMENT
Title Sero-epidemiology of dengue virus infection in Western Terai Region of Nepal
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Date of publication, distribution, etc. c2010.
300 ## - PHYSICAL DESCRIPTION
Extent xiv, 72p. :
500 ## - GENERAL NOTE
General note Thesis Report.
520 ## - SUMMARY, ETC.
Summary, etc. ABSTRACT: Dengue fever (DF) is an emerging mosquito borne disease and important public health problem in low land of Terai region. There are limited information on the prevalence of the disease until now. This study was designed to estimate sero-prevalence of dengue virus infection in the post monsoon period (Aug-Nov) of 2008/2009 in Nepalese patients with fever visiting hospitals of Mahendranagar, Dhangadi and Dang. Serum samples were collected from 283 patients visiting hospital with history of fever & clinically suspected DF. The sero-prevalence of dengue virus specific 1gM was determined by enzyme linked immunosorbent assay (ELISA) kit (PanBio, Australia). The anti-dengue 1gM positivity was found to be 9.8%. The positive dengue cases were higher in female (10.9%) as compared to male (9.0%). Out of total positive cases, the highest positive cases (10.7%) were from age group above 50 years followed by 15-50 years age group with 10.1%. Out of 3 hospitals, the highest positive cases were in Mahakali Zonal Hospital, Mahendranagar (13.3%) followed by Seti Zonal hospital, Dhangadi ( 9.8%). Age and gender were found to be independent predictors. The highest numbers of dengue positive cases were in Ethnic group Brahman/Chherti ( 13.1%) followed by Janajati (5.6%). The highest numbers of dengue positive cases were in occupation group Agriculture (12.0%) followed by student (11.5%). The association between dengue disease and ethnic group & occupation was not statistically significant. Molecular diagnosis based on RT-PCR was also performed to optimize the conditions and confirmatory diagnosis in the acute samples. However, none of the tested sample showed positivity. The 1gM capture ELISA has become the most accepted technique for the diagnosis of dengue in developing countries like Nepal. The sero-prevalence of dengue has marginally increased the concerned authority should initiate extensive surveillance of dengue virus infection and commence an integrated vector control programme in order to abate from a panic viral disease outbreak in the Western Terai region of Nepal in the future. Key words: Dengue fever, 1gM Capture ELISA, RT-PCR, Terai region.
546 ## - LANGUAGE NOTE
Language note Eng.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Dengue fever.
9 (RLIN) 2504
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element 1gM Capture ELISA.
9 (RLIN) 2809
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element RT-PCR.
9 (RLIN) 2810
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Terai region.
9 (RLIN) 2811
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://nhrc.gov.np/contact/">http://nhrc.gov.np/contact/</a>
Link text Visit NHRC Library
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme National Library of Medicine
Koha item type Thesis Report
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
    National Library of Medicine     Nepal Health Research Council Nepal Health Research Council Reference 07/26/2012   THS00234/SHA/2010 THS-00234 07/26/2012 07/26/2012 Thesis Report

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