Study of Severity of Hyperemesis Gravidarum and Associated Maternalfactors.

Thesis Report.

SUMMARY:

BACKGROUND: Hyperemesis Gravidarumis the most severe form of nausea and vomiting. It is one of the most common cause of early pregnancy admissions. Multiple studies have identified various risk factors associated with HG .i.e. non-modifiable risk factors like age , parity and modifiable risk factors like BMI, smoking status, occupations. However the exact etiopathogenesis of HG have not been established. Very few studies have been conducted among Nepalese women with HG. Hence through this research various maternal risk factors among Nepalese women have been identified and severity with HG has been assessed using PUQE scoring.

OBJECTIVES: To find out the relationship of severity of hyperemesis gravidarum with maternal factors.

METHODOLOGY: This is a cross sectional observational study conducted at Paropakar maternity and women's Hospital. Total duration of the study period was for 3 months from February to April 2018.A total of 144 patients meeting the inclusion criteria were included in the study. The severity of the HG was assessed and classified using PUQE scoring. Various maternal demographic, obstetric and personal factors were studied in relation to the incidence and severity of HG.


RESULTS: Obtained data suggest that only moderate to severe HG were admitted in hospital. Most women were housewives, literate, nulliparous at 8-10 weeks of gestation from 20-24 years age group with normal BMI with dysmenorrhea and were nonsmoker.

CONCLUSION: 20-24 years of age, housewives and nulliparity were associated with severe HG in the present study. PUQE score is useful tool for the assessment of severity of HG.