Pearl score in predicting ninety day outcome in patients with acute exacerbation of COPD at tertiary care teaching hospital.

By: Material type: TextTextPublication details: c2019.Description: 74pSubject(s): NLM classification:
  • THS-00558
Online resources: Summary: ABSTRACT: Introduction: Acute exacerbation of COPD is one of the most common reasons for frequent hospital admission. The 90 days post discharge period after acute exacerbation covers the high risk period associated with substantial risk or death, adverse quality of life and high health care costs. The aim of this study was to assess the post discharge 90 days outcome of patients admitted with acute exacerbation of COPD using the PEARL score. Methods: A prospective cohort study was conducted at Tribhuvan University Teaching hospital, Kathmandu, Nepal from September 2018 to August 2019. Patients admitted with acute exacerbation of COPD was stratified using the PEARL score and post discharge 90 days outcome was assessed. Data entry and analysis was done in SPSS version 20.0. Both descriptive and inferential statistics were performed. Univariate analysis was performed using frequency, proportion, mean and standard deviation while bivariate analysis was performed using ANOVA and Chi-square test. Results: A total of 102 patients admitted in medical ward with acute exacerbation of COPD were included in the study. The mean age of patients was 70.54 ± 10.85 years with range from 45 to 98 years. There were 53.9% male patients. The intermediate risk and high risk PEARL groups had the highest proportion of readmission within 90 days of discharge from hospital which was found to be 52.3% and 50% respectively. The high risk PEARL group had the highest proportion of death within 90 days (11.1%). The difference in these outcomes among the PEARL groups was found to be statistically significant (p-value < 0.005). 14 Conclusion: PEARL score is a highly valuable tool that uses routinely available indices to predict 90 days risk of readmission or death in patients admitted with acute exacerbation of COPD. It can effectively guide clinicians to identify the patients at particular risk for clinical decision making, appropriate resource allocation and post discharge planning. Keywords: COPD; exacerbation; PEARL score
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Thesis Report Thesis Report Nepal Health Research Council THS00558/JOS/2019 (Browse shelf(Opens below)) Available THS-00558

Thesis Report.

ABSTRACT:

Introduction: Acute exacerbation of COPD is one of the most common reasons for frequent hospital admission. The 90 days post discharge period after acute exacerbation covers the high risk period associated with substantial risk or death, adverse quality of life and high health care costs. The aim of this study was to assess the post discharge 90 days outcome of patients admitted with acute exacerbation of COPD using the PEARL score.

Methods: A prospective cohort study was conducted at Tribhuvan University Teaching hospital, Kathmandu, Nepal from September 2018 to August 2019. Patients admitted with acute exacerbation of COPD was stratified using the PEARL score and post discharge 90 days outcome was assessed. Data entry and analysis was done in SPSS version 20.0. Both descriptive and inferential statistics were performed. Univariate analysis was performed using frequency, proportion, mean and standard deviation while bivariate analysis was performed using ANOVA and Chi-square test.

Results: A total of 102 patients admitted in medical ward with acute exacerbation of COPD were included in the study. The mean age of patients was 70.54 ± 10.85 years with range from 45 to 98 years. There were 53.9% male patients. The intermediate risk and high risk PEARL groups had the highest proportion of readmission within 90 days of discharge from hospital which was found to be 52.3% and 50% respectively. The high risk PEARL group had the highest proportion of death within 90 days (11.1%). The difference in these outcomes among the PEARL groups was found to be statistically significant (p-value < 0.005). 14

Conclusion: PEARL score is a highly valuable tool that uses routinely available indices to predict 90 days risk of readmission or death in patients admitted with acute exacerbation of COPD. It can effectively guide clinicians to identify the patients at particular risk for clinical decision making, appropriate resource allocation and post discharge planning.

Keywords: COPD; exacerbation; PEARL score

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