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Microbial flora and antimicrobial sensitivity pattern in burn patients.

By:

Sharma, Jyotindra

Publication details: c2000.Description: 78pSubject(s):

NLM classification:

THS00040

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Summary: SUMMARY: Burn causalities are fairly common nowadays in your country and bacterial infection of the burn wound remains a major cause of morbidity and mortality in these patients. This study was conducted to evaluate the incidence of microbial flora and the antibiotic sensitivity pattern in burn wounds at different time during admission, at the Tribhuvan University Teaching Hospital (TUTH) A total of 46 patients were studied for a period of 1 year at TUTU. commonest age group was 21-40 years (52.2%) with the mean age of 33.2 (± 15.9) years. Both male and female patients were nearly equal in number (female to male ratio of 1.2:1). Flame burn was the commonest cause constituting 82.6% burn patients, with 34.8% of patients burned due to stove burst or ignition of clothing while cooking. Accidental burn was the commones mode of burn involving 73.9% of the patients, followed by 19.6% suicidal burn comprising mostly females. Majority of people, 86.8% presented before 24 hours of burn. The mean percentage of burn surface area was 40% (± 28) of Total Body Surface Area (TBSA). Involvement of body areas by burn was more or less same in all parts except relatively lower incidence in lower limbs. The overall mortality was 32.6% with the first week mortality of 26% and 6.6% afterwards. The mean burn size percentage for overall mortality was 72.8%. On day 1, only 21.7% of swab samples grew organisms while there was not a single growth from the tissue sample. On day 7,76.5% of swab samples grew organisms while only 14.7% people grew organisms while only 10% tissue samples grew organisms. There was a statistically significant difference in the growth of organisms both in the tissue and the swab samples in different weeks and between tissue and swab in each week (p-value of <0.05). In total, 26.8% growth was seen in both tissue and swab on all the samples (Days 1, 7, 14-21). Staphylococcus aureus (10.9%) was the commonest isolate in both tissue.

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Holdings
Item type	Current library	Call number	Status	Date due	Barcode
Thesis Report	Nepal Health Research Council Reference	THS-00040/SHA/2000 (Browse shelf(Opens below))	Available		THS-00040

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Previous	THS-00037/ JHA/2000 Study of incidence of peritonitis in patients undergoing peritoneal dialysis.	THS-00038/TAB/2000 Effect on intra qcular pressure and hemodynamic response with endotrachealintumation vs laryngeal mask airway insertion in children.	THS-00039/SAH/2000 Preterm labor and associated factors.	THS-00040/SHA/2000 Microbial flora and antimicrobial sensitivity pattern in burn patients.	THS-00041/K.C./2000 Contributing factors unmet need of family planning among multigravida women attending at koshi zonal hospital.	THS-00042/SED/2000 Maternal morbidity in vaginal delivery with episiotomy.	THS-00043/PRA/2000 Determining factors of anemia in pregnant women attending antenatal clinic.	Next

Thesis Report.

SUMMARY: Burn causalities are fairly common nowadays in your country and bacterial infection of the burn wound remains a major cause of morbidity and mortality in these patients. This study was conducted to evaluate the incidence of microbial flora and the antibiotic sensitivity pattern in burn wounds at different time during admission, at the Tribhuvan University Teaching Hospital (TUTH) A total of 46 patients were studied for a period of 1 year at TUTU. commonest age group was 21-40 years (52.2%) with the mean age of 33.2 (± 15.9) years. Both male and female patients were nearly equal in number (female to male ratio of 1.2:1). Flame burn was the commonest cause constituting 82.6% burn patients, with 34.8% of patients burned due to stove burst or ignition of clothing while cooking. Accidental burn was the commones mode of burn involving 73.9% of the patients, followed by 19.6% suicidal burn comprising mostly females. Majority of people, 86.8% presented before 24 hours of burn. The mean percentage of burn surface area was 40% (± 28) of Total Body Surface Area (TBSA). Involvement of body areas by burn was more or less same in all parts except relatively lower incidence in lower limbs. The overall mortality was 32.6% with the first week mortality of 26% and 6.6% afterwards. The mean burn size percentage for overall mortality was 72.8%. On day 1, only 21.7% of swab samples grew organisms while there was not a single growth from the tissue sample. On day 7,76.5% of swab samples grew organisms while only 14.7% people grew organisms while only 10% tissue samples grew organisms. There was a statistically significant difference in the growth of organisms both in the tissue and the swab samples in different weeks and between tissue and swab in each week (p-value of <0.05). In total, 26.8% growth was seen in both tissue and swab on all the samples (Days 1, 7, 14-21). Staphylococcus aureus (10.9%) was the commonest isolate in both tissue.

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