Identification of the mutation in KAT and INH a genes of isoniazid resistant mycobacterium tuberculosis.
ABSTRACT: Alteration of katG gene spanning codons 275,309,315,328,463,516 and inhA gene at upstream positions -8,-15,-24 or codons 16,21,94,95 have been reported frequently as the root causes of isoniazid resistance in Mycobacterium tuberculosis. In the present study, 29 multi-drug resistant/isonia...
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